What is the life expectancy of Ehlers-Danlos syndrome?
The overall life expectancy of patients with vEDS is dramatically shortened, largely as a result of vascular rupture, with a median life span of 48 years (range, 6–73 years). In addition, the prognosis after treatment is still poor.
How do I know if my cat has EDS?
This results in a variety of clinical signs including loose, hyperextensible, fragile skin, joint laxity and other connective tissue dysfunctions. Clinical signs include fragile skin from the time of birth, wounds that heal with thin scars, delayed wound healing, pendulous skin, hematoma and hygroma formation.
Is Ehlers-Danlos serious?
Vascular Ehlers-Danlos syndrome can weaken your heart’s largest artery (aorta), as well as the arteries to other regions of your body. A rupture of any of these larger blood vessels can be fatal. The vascular type can also weaken the walls of the uterus or large intestines — which also may rupture.
Can someone with EDS live a long life?
It is often associated with a shortened lifespan. Among affected people diagnosed as the result of a complication, 25% have experienced a significant medical complication by age 20 and more than 80% by age 40. The median life expectancy for people affected by vascular EDS is 48 years.
What happens with EDS as you get older?
Everyone’s bones become weaker with age. In EDS patients with hypermobile joints, weakening bones can make the symptoms of the disease more severe as it progresses. Bones and joints that were previously dislocated may also break more often. The severe forms of EDS (vascular and cardiac-valvular) can affect lifespan.
What causes death with EDS?
The most serious complications include a rupture of a viscus or vascular rupture with or without mural dissection. Death may result from internal hemorrhage. This report describes three cases of sudden and unexpected death caused by EDS type IV.
Can you live a long life with Ehlers-Danlos?
The long-term outlook (prognosis) for people with vascular Ehlers-Danlos syndrome is generally poor. It is often associated with a shortened lifespan. Among affected people diagnosed as the result of a complication, 25% have experienced a significant medical complication by age 20 and more than 80% by age 40.
Can Ehlers-Danlos be fatal?
Vascular Ehlers-Danlos syndrome can weaken your heart’s largest artery (aorta), as well as the arteries to other regions of your body. A rupture of any of these larger blood vessels can be fatal.
Does EDS shorten lifespan?
Patients with kyphoscoliotic EDS — whose hallmark is a sideways curvature of the spine in combination with a hunched back — also may have a reduced life expectancy. This can be because of vascular symptoms, or increased risk of lung problems. For people with other types of EDS, life expectancy is usually not affected.
What is the life expectancy of someone with hypermobile Ehlers-Danlos syndrome?
Life span is often affected. Currently, the median life span is about 51 years—within a wide range from 10 to 80 years—and it is influenced by the nature of the particular COL3A1 variant.
Does EDS cause early death?
Although all types of EDS are potentially life-threatening, most people have a normal lifespan. Those with blood vessel fragility, though, have a high risk of fatal complications, including spontaneous arterial rupture, which is the most common cause of sudden death.
Does hypermobile EDS affect life expectancy?
The most common types of EDS (classical, classical-like, and hypermobile) do not greatly affect life expectancy. However, symptoms may become more severe as patients age and joints that have been dislocated multiple times become painful. Everyone’s bones become weaker with age.
Does Ehlers-Danlos cause early death?
About 80% of patients with vascular Ehlers-Danlos syndrome will experience a major health event by age 40 and the life expectancy is shortened, with an average age of death of 48 years.
How long do people with EDS live?
The median life expectancy for individuals with vascular EDS is around 48 years. Patients with kyphoscoliotic EDS — whose hallmark is a sideways curvature of the spine in combination with a hunched back — also may have a reduced life expectancy.
How long can someone with EDS live?
Patients with the classical and hypermobility forms of Ehlers-Danlos syndrome have a normal life expectancy. About 80% of patients with vascular Ehlers-Danlos syndrome will experience a major health event by age 40 and the life expectancy is shortened, with an average age of death of 48 years.